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As weight loss medications gain popularity, some runners face performance issues due to side effects. Keri M., a marathon runner, experienced nausea and energy deficits while on GLP-1 treatment during a race. The use of these medications has surged, with many users not classified as overweight. Experts are divided on the compatibility of GLP-1 drugs with endurance sports, with some advising caution. While some athletes attempt microdosing to mitigate side effects, this practice lacks clinical validation. The impact of GLP-1 on heart rate and exercise performance remains under-researched, prompting nutritionists to recommend avoiding these treatments during intense training periods.