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Pickles can spoil quickly if not stored properly after opening. They should be refrigerated immediately and kept submerged in liquid. Proper storage can extend their shelf life from one to three months, depending on the preparation method. Common mistakes include leaving vegetables above the liquid level and using dirty utensils, which can introduce bacteria. Signs of spoilage include off smells, mold, and changes in texture. It's crucial to check pickles before consumption and discard them if any spoilage signs are present.