STUDIU | Îmbătrânirea ar putea începe în măduva osoasă

A recent study on mice reveals how aging blood stem cells may lead to systemic changes associated with aging, highlighting the role of the SIRT3 protein. Researchers found that aged hematopoietic stem cells produce more inflammatory immune cells, affecting distant organs. Genetic modifications to increase SIRT3 levels in these cells improved the health and function of young mice's immune systems. The study suggests that SIRT3 could prevent excessive inflammatory cell production, but results are preliminary and require caution in interpretation, especially regarding human applications.