Cum distruge microglia neuronii încă vii în scleroza laterală amiotrofică

Researchers at the Salk Institute have identified a mechanism by which microglia eliminate functional motor neurons in mice with amyotrophic lateral sclerosis (ALS). This study reveals that microglia use TAM receptors to recognize and destroy certain neurons, contributing to disease progression. The findings suggest potential therapeutic strategies for ALS and other neurodegenerative diseases. The study highlights the abnormal activation of microglia in ALS and its role in neuron loss, indicating that TAM signaling may also be relevant in conditions like Alzheimer's and cancer.