Anestezia cu ketamină produce schimbări surprinzătoare în creier. Efectul apare doar la femele, într-un studiu pe șoareci

Researchers found that ketamine anesthesia increases brain plasticity and neural remodeling in female mice, revealing complex effects on the brain. The study showed that microglia interacted more with neurons in females, promoting synapse formation. The role of corticosterone was significant, as it activated genes in microglia that enhance neuron interaction. Notably, this plasticity was not observed in male mice, suggesting potential differences in brain remodeling mechanisms. These findings may impact future research on ketamine's therapeutic use for depression, highlighting the need for further studies on gender differences in drug effects.